Projekte
- A duck hepatitis B virus strain with a knockout mutation in the putative X ORF shows similar infectivity and in vivo growth characteristics to wildtype virus
- Characterization of nonconventional hepatitis B viruses lacking the core promoter
- Cholesterol is essential for the structural integrity and infectivity of hepatitis B viruses
- Deficiency in virion secretion and decreased stability of the hepatitis B virus immune escape mutant G145R
- Dissecting the entry mechanism of hepatitis B viruses: pH-independent entry and sequential endosomal sorting are the major determinants
- Functional characterization of the interaction between human La and hepatitis B virus RNA
- Itinerary of hepatitis B viruses: Delineation of restriction points critical for infectious entry
- Mx1 GTPase accumulates in distinct nuclear domains and inhibits influenza A virus in cells that lack promyelocytic leukaemia protein nuclear bodies
- New hepatitis B virus of cranes that has an unexpected broad host range
- Nuclear trafficking of La protein depends on a newly identified nucleolar localization signal and the ability to bind RNA
- Radiation induced polyploidization depends on the p53 status
- Regulation and function of p53 and ∆p53 in the ATM/ATR-mediated intra-S-phase checkpoint
- Regulation of homeodomain-interacting protein kinase 2 (HIPK2) effector function through dynamic small ubiquitin-related modifier-1 (SUMO-1) modification.
- Reorganisation of the endomembranes during Hepatitis B Viral morphogenesis: virus factories?
- Selection of a secretion-incompetent mutant in the serum of a patient with severe hepatitis B
- Small ubiquitin-related modifiers: A novel and independent class of autoantigens in primary biliary cirrhosis.
- SPOC1, a novel PHD-finger protein: association with residual disease and survival in ovarian cancer.
- Spread of hepatitis B viruses in vitro requires extracellular progeny and may be codetermined by polarized egress
- The Hepatitis B Virus PRE contains a splicing regulatory element
- The La motif and the RNA recognition motifs of human La autoantigen contribute individually to RNA recognition and subcellular localization
- Viral induced modulation of signal transduction pathways
Abteilungen & Forschungsgruppen
Allgemeine Virologie
Leiter
Prof. Dr. Hans Will
Martinistraße 52
20251 Hamburg
Tel.: 040/48051-221
Sekretariat
Dr. Andreas Mund
Martinistraße 52
20251 Hamburg
Tel.: 040/48051-229
