Publikationen

Blandino G, Deppert W, Hainaut P, Levine A, Lozano G, Olivier M, Rotter V, Wiman K, Oren M. (2012). Mutant p53 protein, master regulator of human malignancies: a report on the fifth Mutant p53 Workshop. Cell Death Differ. 19(1):180-3

Helmbold H, Galderisi U, Bohn W (2012). The switch from Rb1/p105 to Rb2/p130 in DNA damage and cellular senescence. J Cell Physiol. 227(2):508-13

Hirner H, Günes C, Bischof J, Wolff S, Grothey A, Kühl M, Oswald F, Wegwitz F, Bösl M, Tauzold A, Henne-Bruns D, Peifer C, Leithäuser F, Deppert W, Knippschild W (2012). Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivo PLoS ONE 7(1):e29709

Deppert W, Tolstonog GV. (2011). P53 Models for Mammary Carcinogenesis. In p53 in the Clinics; Klas Wiman (Editor), Pierre Hainaut (Editor), Magali Olivier (Editor), Springer, in press

Gerstel D, Wegwitz F, Jannasch K, Ludewig P, Scheike K, Alves F, Beauchemin N, Deppert W, Wagener C, Horst A. (2011). CEACAM1 creates a pro-angiogenic tumor microenvironment that supports tumor vessel maturation. Oncogene. 2011 May 2. [Epub ahead of print]

Helmbold H, Deppert W, Bohn W (2011). Epigenetic control in cellular senescence. Cancer Epigenetics: Biomolecular Therapeutics in Human Cancer by Antonio Giordano (Editor), Marcella Macaluso, PhD (Editor), Wiley 2011

Heinlein C, Deppert W, Braithwaite AW, Speidel D. (2010). A rapid and optimization-free procedure allows the in vivo detection of subtle cell cycle and ploidy alterations in tissues by flow cytometry. Cell Cycle. 2010 Sep;9(17):3584-90.

Hildebrand J, Rütze M, Gallinat S, Wenck H, Deppert W, Grundhoff A, Knott A (2010). A comprehensive analysis of microRNA expression during human keratinocyte differentiation in vitro and in vivo. J Invest Dermatol. 2010 Sep 9.

Kim E, Wüstenberg R, Warnecke G, Bücker EM, Pettkus N, Speidel D, Rohde V, Schulz-Schaeffer W, Deppert W, Giese A (2010). Chloroquine Activates the p53 Pathway and Induces Apoptosis in Human Glioma Cells. Neuro-Oncology (adv. access Jan. 27, 2010)

Ruetze M, Gallinat S, Wenck H, Deppert W, Knott A (2010). In situ localization of epidermal stem cells using a novel multi epitope ligand cartography approach. Integr Biol (Camb). 2010 Jun;2(5-6):241-9. Epub 2010 Jun 8

Tolstonog GV, Deppert W. (2010). Metabolic sensing by p53: Keeping the balance between life and death. PNAS published ahead of print July 20, 2010, doi:10.1073/pnas.1007945107

Utz AC, Hirner H, Blatz A, Hillenbrand A, Schmidt B, Deppert W, Henne-Bruns D, Fischer D, Thal DR, Leithäuser F, Knippschild U. (2010). Analysis of cell type-specific expression of CK1 epsilon in various tissues of young adult BALB/c Mice and in mammary tumors of SV40 T-Ag-transgenic mice. J Histochem Cytochem. 2010 Jan;58(1):1-15. Epub 2009 Sep 15.

Wegwitz F, Kluth MA, Mänz C, Otto B, Gruner K, Heinlein C, Kühl M, Warnecke G, Schumacher U, Deppert W, Tolstonog GV (2010). Tumorigenic WAP-T Mouse Mammary Carcinoma Cells: A Model for a Self-Reproducing Homeostatic Cancer Cell System. PLoS ONE Aug 11;5(8). pii: e12103

Brázdová M., Quante T., Tögel L., Walter K., Loscher C., Tichý V., Činčárová L., Deppert W., Tolstonog G.V. (2009). Modulation of gene expression in U251 glioblastoma cells by binding of mutant p53 R273H to intronic and intergenic sequences. Nucleic Acids Res, 37(5):1486-500. Epub 2009 Jan 12

Deppert W. (2009). Alternatively Spliced p53 Isoforms: Alternative Views or Alternative Functions? Cell Cycle, 8(11):1645

Helmbold H., Kömm N., Deppert W., Bohn W. (2009). Rb2/p130 is the Dominating Pocket Protein in the p53-p21 DNA-Damage Response Pathway Leading to Senescence. Oncogene. 2009 Oct 1;28(39):3456-67. Epub 2009 Aug 3.

Hermannstädter A., Ziegler C., Kühl M., Deppert W., Tolstonog G. (2009). Wild-Type p53 enhances the efficiency of Simian Virus 40 Mediated Cellular Transformation. J Virol. 2009 Oct;83(19):10106-18. Epub 2009 Jul 22.

Jannasch K., Dullin C., Heinlein C., Krepulat F., Wegwitz F., Deppert W., Alves F. (2009). Detection of different tumor growth kinetics in single transgenic mice with oncogene induced mammary carcinomas by flat-panel Volume Computed Tomography (fpVCT). Int J Canc, 125(1):62-70

Reimer R., Helmbold H., Szalay B., Hagel C., Deppert W., Bohn W. (2009). Nestin Modulates Glucocorticoid Receptor Function by Cytoplasmic Anchoring. PLoS One, Jun 29;4(6):e6084

Tolstonog GV, Deppert W. (2009). The p53 transcriptional synapse: activation on demand. Nat Struct Mol Biol 16(9):910-5

Weise JM, Günes C (2009). Differential Regulation of Human and Mouse Telomerase Reverse. Mol. Reprod. Dev.76(3):309-17

Deppert W. (2008). SIRT1 protein levels in cancer: Tuning SIRT1 to the needs of a cancer cell. Cell Cycle 7(19):2947-8. Epub 2008 Oct 1

Engelmann A., Speidel D., Deppert W., Stocking C. (2008). Gadd45ß is a pro-survival factor associated with stress-resistant tumors. Oncogene 27:1429-38

Galderisi U, Helmbold H, Squillaro T, Alessio N, Komm N., Khadang B., Cipollaro M., Bohn W., Giordano A. (2008). In vitro senescence of rat mesenchymal stem cells is accompanied by downregulation of stemness-related and DNA damage repair genes. Stem Cells Dev 2008 Dec 19. [Epub ahead of print]

Heinlein C., Krepulat F., Löhler J., Speidel D., Deppert W., Tolstonog G. (2008). Mutant p53R270H gain of function phenotype in a mouse model. Int. J. Cancer 122(8):1701-9