Publikationen
Anzahl Suchtreffer: 24
Zelluläre Virusabwehr
2011
Alkharsah KR, Singh VV, Bosco R, Santag S, Grundhoff A, Konrad A, Stürzl M, Wirth D, Dittrich-Breiholz O, Kracht M, Schulz TF (2011). Deletion of Kaposi's Sarcoma-Associated Herpesvirus FLICE Inhibitory Protein, vFLIP, from the Viral Genome Compromises the Activation of STAT1-Responsive Cellular Genes and Spindle Cell Formation in Endothelial Cells. J Virol. 2011 Oct;85(19):10375-88. Epub 2011 Jul 27.
(Abstract)Grundhoff A (2011). Computational prediction of viral miRNAs Methods Mol Biol. 2011;721:143-52.
(Abstract)Grundhoff A, Sullivan CS (2011). Virus-encoded microRNAs Virology. 2011 Mar 15;411(2):325-43. Epub 2011 Jan 31.
(Abstract)Hildebrand J, Rütze M, Walz N, Gallinat S, Wenck H, Deppert W, Grundhoff A, Knott A (2011). A comprehensive analysis of microRNA expression during human keratinocyte differentiation in vitro and in vivo. J Invest Dermatol. 2011 Jan;131(1):20-9. Epub 2010 Sep 9
(Abstract)Hussain M, Torres S, Schnettler E, Funk A, Grundhoff A, Pijlman GP, Khromykh AA, Asgari S. (2011). West Nile virus encodes a microRNA-like small RNA in the 3' untranslated region which up-regulates GATA4 mRNA and facilitates virus replication in mosquito cells. Nucleic Acids Res. 2011 Nov 12. [Epub ahead of print]
(Abstract)Yakushko Y, Hackmann C, Günther T, Rückert J, Henke M, Koste L, Alkharsah K, Bohne J, Grundhoff A, Schulz TF, Henke-Gendo C (2011). Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome contains a duplication of a long unique-region fragment within the terminal repeat region. J Virol. 2011 May;85(9):4612-7. Epub 2011 Feb 9.
(Abstract)2010
El-Armouche, A., Schwoerer, A.P., Neuber, C., Emmons, J., Biermann, D., Christalla, T., Grundhoff, A., Eschenhagen, T., Zimmermann, W.H., Ehmke, H. (2010). Common microRNA signatures in cardiac hypertrophic and atrophic remodeling induced by changes in hemodynamic load. PLoS One 5(12): e14263.
Fischer, N., Brandner, J., Fuchs, F., Moll, I., Grundhoff, A. (2010). Detection of the Merkel cell polyomavirus (MCPyV) in Merkel cancer cell lines: cell line morphology does not reflect the presence of the virus. Int J Cancer 126(9):2133-42. Epub 2009 Sep 8.
Günther, T., Grundhoff, A. (2010). The Epigenetic Landscape of Latent Kaposi Sarcoma-associated Herpesvirus Genomes. PLoS Pathog, in press.
Seto, E., Moosmann, A., Grömminger, S., Walz, N., Grundhoff, A., Hammerschmidt, W. (2010). Micro RNAs of Epstein-Barr Virus Promote Cell Cycle Progression and Prevent Apoptosis of Primary Human B Cells. PLoS Pathog 6(8): e1001063. doi:10.1371/journal.ppat.1001063
Walz, N., Christalla, T., Tessmer, U., Grundhoff, A. (2010). A global analysis of evolutionary conservation among known and predicted gammaherpesvirus microRNAs. Virol. 2010 Jan;84(2):716-28. Epub 2009 Nov 4.
2009
Grundhoff, A. (2009). Micro Mining: Computational Approaches to miRNA Discovery. In Regulation of Gene Expression by Small RNAs. Gaur, R.K. and Rossi, J.J, eds. (CRC Press), pp. 1-19.
Sullivan, C.S., Sung, C.K., Pack, C.D, Grundhoff., A., Lukacher, A.E., Benjamin, T.L. and Ganem, D. (2009). Murine Polyomavirus encodes a microRNA that cleaves early RNA transcripts but is not essential for experimental infection. Virology 2009 Mar 9. (Epub ahead of print)
2007
Sullivan, C. S. and Grundhoff, A. (2007). Identification of viral miRNAs. In Methods in Enymology (427): MicroRNA Methods. Rossi, J.J. and Hannon G.J., eds. (Elsevier Inc.), pp. 3-23.
2006
Grundhoff A., Sullivan C.S. and Ganem D. (2006). A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses RNA 12: 733-750
Sullivan CS, Grundhoff A, Tevethia S, Treisman R, Pipas JM, Ganem D. (2006). Expression and function of microRNAs in viruses great and small Cold Spring Harb Symp Quant Biol. 2006;71:351-6
Will H. and Grundhoff A. (2006). Fighting Viral Hepatitis with small RNAs J Hepatol. 44: 1009-1011
Ziegelbauer, J., Grundhoff, A., and Ganem, D. (2006). Exploring the DNA binding interactions of the Kaposi's sarcoma-associated herpesvirus lytic switch protein by selective amplification of bound sequences in vitro. J Virol 80, 2958-2967
2005
Bechtel J., Grundhoff A. and Ganem D. (2005). RNAs in the virion of Kaposi's Sarcoma-Associated Herpesvirus J Virol. 79(16):10138-46
Sullivan C.S., Grundhoff A., Pipas J.M. and Ganem D. (2005). SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells Nature 435(7042):682-6
2004
Grundhoff A. and Ganem D. (2004). Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis J. Clin. Invest. 113 (1): 124-36
2003
Grundhoff A. and Ganem D. (2003). LANA mediates replication of terminal repeat-containing plasmids J. Virol. 77: 2779-2783
2001
Grundhoff A. and Ganem D. (2001). Mechanisms Governing Expression of the v-FLIP Gene of Kaposi's Sarcoma-Associated Herpesvirus J. Virol. 75:1857-1863
1999
Grundhoff A., Kremmer E., Tureci O., Glieden A., Gindorf C., Atz J., Mueller-Lantzsch N., Schubach WH and Grasser F.A. (1999). Characterization of DP103, a novel DEAD box protein that binds to the Epstein-Barr virus nuclear proteins EBNA2 and EBNA3C J. Biol. Chem. 274 (27):19136-44
Anzahl Suchtreffer: 24
Abteilungen & Forschungsgruppen
Zelluläre Virusabwehr
Leiter
Dr. rer. nat. Adam Grundhoff
Martinistraße 52
20251 Hamburg
Tel.: 040/48051-275





