Mechanisms of Antiviral Defense

Our research is focused on Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV), two human gamma-herpesviruses which are strongly linked to certain cancers. We investigate how these viruses establish and maintain a long-lasting (i.e., latent) infection and how such infections might predispose the host to the development of tumors.

Recent Publications

Fischer, N., Brandner, J., Fuchs, F., Moll, I., Grundhoff, A. (2010). Detection of the Merkel cell polyomavirus (MCPyV) in Merkel cancer cell lines: cell line morphology does not reflect the presence of the virus. Int J Cancer 126(9):2133-42. Epub 2009 Sep 8.

Günther, T., Grundhoff, A. (2010). The Epigenetic Landscape of Latent Kaposi Sarcoma-associated Herpesvirus Genomes. PLoS Pathog, in press.

Walz, N., Christalla, T., Tessmer, U., Grundhoff, A. (2010). A global analysis of evolutionary conservation among known and predicted gammaherpesvirus microRNAs. Virol. 2010 Jan;84(2):716-28. Epub 2009 Nov 4.

List of all publications of this department

Departments and Research Groups