Publikationen

Anzahl Suchtreffer: 117

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Antivirale Strategien

2019

Chemnitz J, Pieper D, Stich L, Schumacher U, Balabanov S, Spohn M, Grundhoff A, Steinkasserer A, Hauber J, Zinser E (2019). The acidic protein rich in leucines Anp32b is an immunomodulator of inflammation in mice. Sci Rep. 2019 Mar 19;9(1):4853.

2018

Bialek JK, Walther T, Hauber J, Lange UC (2018). CRISPR-Cas9-based Genome Engineering to Generate Jurkat Reporter Models for HIV-1 Infection with Selected Proviral Integration Sites. J Vis Exp. 2018 Nov 14;(141).

Brunnemann AK, Hoffmann A, Deinhardt-Emmer S, Nagel CH, Rose R, Fickenscher H, Sauerbrei A, Krumbholz A. (2018). Relevance of non-synonymous thymidine kinase mutations for antiviral resistance of recombinant herpes simplex virus type 2 strains. Antiviral Res. 2018 Apr;152:53-57.

Czechowicz JS, Nagel C-H, Voges M, Spohn M, Eibl MM, Hauber J. (2018). Interaction between the cellular E3 ubiquitin ligase SIAH-1 and the viral immediate-early protein ICP0 enables efficient replication of Herpes Simplex Virus type 2 in vivo. PLoS One. 2018 Aug 6;13(8):e0201880.

Hauber I, Beschorner N, Schrödel S, Chemnitz J, Kröger N, Hauber J, Thirion C (2018). Improving Lentiviral Transduction of CD34+ Hematopoietic Stem and Progenitor Cells. Hum Gene Ther Methods. 2018 Apr;29(2):104-113.

Lange UC, Bialek JK, Walther T, Hauber J (2018). Pinpointing recurrent proviral integration sites in new models for latent HIV-1 infection. Virus Res. 2018 Apr 2;249:69-75.

2017

Dunay GA, Solomatina A, Kummer S, Hüfner A, Bialek JK, Eberhard JM, Tolosa E, Hauber J, Schulze zur Wiesch J (2017). Assessment of the HIV-1 Reservoir in CD4+ Regulatory T Cells by a Droplet Digital PCR Based Approach. Virus Res. 2017 Aug 15;240:107-111.

Karpinski J, Schneider M, Lansing F, Hauber J, Buchholz F. (2017). Designer-Rekombinasen für präzises Genome Editing. BIOspektrum. 2017 Mar; 23(2):151–154.

2016

Bialek JK, Dunay GA, Voges M, Schäfer C, Spohn M, Stucka R, Hauber J, Lange UC (2016). Targeted HIV-1 Latency Reversal Using CRISPR/Cas9-Derived Transcriptional Activator Systems. PLoS One. 11:e0158294.

Buchholz F, Hauber J. (2016). Antiviral Therapy of Persitstent Viral Infection Using Genome Editing. Curr Opin Virol. 20:85-91.

Dunay G, Tóth I, Eberhard JM, Degen O, Tolosa E, van Lunzen J, Hauber J, Schulze zur Wiesch J (2016). Parallel Assessment of Th17 Cell Frequencies by Surface Marker Co-Expression Versus Ex Vivo IL-17 Production in HIV-1 Infection. Cytometry B Clin Cytom. 90:486-492.

Gollnest T, Dinis de Oliveira T, Rath A, Hauber I, Schols D, Balzarini J, Meier C. (2016). Membrane-permeable Triphosphate Prodrugs of Nucleoside Analogues. Angew Chem Int Ed Engl. 55:5255-8.

Karpinski J, Hauber I, Chemnitz J, Schäfer C, Paszkowski-Rogacz M, Chakraborty D, Beschorner N, Hofmann-Sieber H, Lange UC, Grundhoff A, Hackmann K, Schrock E, Abi-Ghanem J, Pisabarro MT, Surendranath V, Schambach A, {...} Hauber J, Buchholz F. (2016). Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity. Nat Biotechnol. 34:401-409.

Martinez-Rocha AL, Woriedh M, Chemnitz J, Willinghmann P, Kröger C, Hauber J, Schäfer W. (2016). Posttranslational Hypusination of the Eukaryotic Translation Initiation Factor-5A Regulates Fusarium graminearum Virulence. Scientific Reports 6:4698.

Meinke G, Bohm A, Hauber J, Pisabarro MT, Buchholz F (2016). Cre Recombinase and Other Tyrosine Recombinases. Chem Rev. 2016 Oct 26;116(20):12785-12820.

Mock U, Hauber I, Fehse B. (2016). Digital PCR to Assess Gene-Editing Frequencies (GEF-dPCR) Mediated by Designer Nucleases. Nature Protocols. 11:598-615.

Schröder M, Kolodzik A, Windshügel B, Krepstakies M, Priyadarshini P, Hartjen P, van Lunzen J, Rarey M, Hauber J, Meier C. (2016). Linker-Region Modified Derivatives of the Deoxyhypusine Synthase Inhibitor CNI-1493 Suppress HIV-1 Replication. Arch Pharm (Weinheim) 349, 91-103.

Voges M, Schneider C, Sinn M, Hartig J, Reimer R, Hauber J, Moelling K (2016). Abolishing HIV-1 Infectivity Using a Polypurine Tract-Specific G-Quadruplex-Forming Oligonucleotide. BMC Infect Dis. 16:358.

2015

Geissler R, Hauber I, Funk N, Richter A, Behrens M, Renner I, Chemnitz J, Hofmann-Sieber H, Baum H, van Lunzen J, Boch J, Hauber J, Behrens S-E. (2015). Patient-adapted, Specific Activation of HIV-1 by Customized TAL Effectors (TALEs), a Proof of Principle Study. Virology. 2015 Oct 13;486:248-254.

Han Z, Sakai N, Böttger LH, Klinke S, Hauber J, Trautwein AX, Hilgenfeld R. (2015). Crystal Structure of the Peroxo-diiron(III) Intermediate of Deoxyhypusine Hydroxylase, an Oxygenase Involved in Hypusination. Structure. 2015 May 5;23(5):882-92.

Karimova M, Beschorner N, Dammermann W, Chemnitz J, Indenbirken D, Bockmann J-H, Grundhoff A, Lüth L, Buchholz F, Schulze zur Wiesch J, Hauber J (2015). CRISPR/Cas9 Nickase-Mediated Disruption of Hepatitis B Virus Open Reading Frame S and X. Sci Rep. 2015 Sep 3;5:13734.

Mock U, Machowicz R, Hauber I, Horn S, Abramowski P, Berdien B, Hauber J and Fehse B. (2015). mRNA Transfection of a Novel TAL Effector Nuclease (TALEN) Facilitates Efficient Knockout of HIV Coreceptor CCR5. Nucleic Acids Res. 2015 Jun 23;43(11):5560-71.

Pällmann N, Braig M, Sievert H, Preukschas M, Hermans-Borgmeyer I, Schweizer M, Nagel CH, Neumann M, Wild P, Haralambieva E, Hagel C, Bokemeyer C, Hauber J, Balabanov S (2015). Biological Relevance and Therapeutic Potential of the Hypusine Modification System. J Biol Chem. 2015 Jul 24;290(30):18343-60.

Thierry S, Benleulmi MS, Sinzelle L, Thierry E, Calmels C, Chaignepain S, Waffo-Teguo P, Merillon JM, Budke B, Pasquet JM, Litvak S, Ciuffi A, Sung P, Connell P, Hauber I, Hauber J, Andreola ML, Delelis O, Parissi V (2015). Dual and Opposite Effects of hRAD51 Chemical Modulation on HIV-1 Integration. Chem Biol. 2015 Jun 18;22(6):712-23.

2014

Cosgun KN, Rahmig S, Mende N, Reinke S, Hauber I, Schäfer C, Petzold A, Weisbach H, Heidkamp G, Purbojo A, Cesnajevar R, Platz A, Bornhäuser M, Schmitz M, Dudziak D, Hauber J, Kirberg J, Waskow C (2014). Kit Regulates HSC Engraftment Across the Human-Mouse Species Barrier. Cell Stem Cell,15:227-38.

Anzahl Suchtreffer: 117

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