Scientific HPI Publications on COVID-19 (SARS-CoV-2)

Bunders M, Altfeld M (2020). Implications of sex differences in immunity for SARS-CoV-2 pathogenesis and design of therapeutic intervention. REVIEW: Immunity. 2020 Sep 15;53(3):487-495.

Günther S, Reinke PYA, Oberthuer D, (...), Schmidt C, Schubert R, Han H, Krichel B, Fernández-García Y, Escudero-Pérez B, Günther A, Turk D, Uetrecht C, (...), Hilgenfeld R, Chapman HN, Pearson AR, Betzel C, Meents A (2020). Catalytic cleavage of HEAT and subsequent covalent binding of the tetralone moiety by the SARS-CoV-2 main protease. bioRxiv [Preprint] 2020.05.02.043554; doi:

Günther T, Czech-Sioli M, Indenbirken D, Robitaille A, Tenhaken P, Exner M, Ottinger M, Fischer N, Grundhoff A, Brinkmann MM (2020). SARS-CoV-2 outbreak investigation in a German meat processing plant. EMBO Mol Med. 2020 Oct 4:e202013296.

Krichel B, Bylapudi G, Schmidt C, Blanchet C, Schubert R, Brings L, Koehler M, Zenobi R, Svergun D, Lorenzen K, Madhugiri R, Ziebuhr J, Uetrecht C (2020). Hallmarks of Alpha - and Betacoronavirus non-structural protein 7+8 complexes. bioRxiv [Preprint]. 2020 Sep 30:2020.09.30.320762. Available at bioRxiv: PREPRINT

Mousavizadeh L, Ghasemi S. Genotype and phenotype of COVID-19: Their roles in pathogenesis. J Microbiol Immunol Infect. 2020 Mar 31.

Pfefferle S, Guenther T, Kobbe R, Czech-Sioli M, Noerz D, Santer R, Oh J, Kluge S, Oestereich L, Peldschus K, Indenbirken D, Huang J, Grundhoff A, Aepfelbacher M, Knobloch J, Luetgehetmann M, Fischer N (2020). SARS-CoV-2 variant tracing within the first COVID-19 clusters in Northern Germany. Clin Microbiol Infect. 2020 Sep 29:S1198-743X(20)30587-5.

Pfefferle S, Guenther T, Puelles V, Heinrich F, Noerz D, Czech-Sioli M, Carstens A, Krasemann S, Wong M, Oestereich L, Magnus T, Allweiss L, Edler C, Schroeder AS, Dandri M, Huber T, Glatzel M, Pueschel K, Grundhoff A, Luetgehetmann M, Aepfelbacher M, Fischer N (2020). SARS-CoV-2 infects carotid arteries: implications for vascular disease and organ injury in COVID-19. bioRxiv [Preprint] 2020.10.10.334458. Available at bioRxiv:

Pfefferle S, Huang J, Nörz D, Indenbirken D, Lütgehetmann M, Oestereich L, Günther T, Grundhoff A, Aepfelbacher M, Fischer N (2020). Complete Genome Sequence of a SARS-CoV-2 Strain Isolated in Northern Germany. Microbiol Resour Announc. 2020 Jun 4;9(23):e00520-20.

Schroeder M, Tuku B, Jarczak D, Nierhaus A, Bai T, Jacobsen H, Zickler M, Mueller Z, Stanelle-Bertram S, Meinhardt A, Aberle J, Kluge S, Gabriel G (2020). The majority of male patients with COVID-19 present low testosterone levels on admission to Intensive Care in Hamburg, Germany: a retrospective cohort study. medRxiv 2020.05.07.20073817 (May 11, 2020). Available at medRxiv: PREPRINT *

* Study based on insights from: Chen Y, Bai T, Beck S, Stanelle-Bertram S, Chen T, Dong J, Yang J, Wang L, Wang D, Shu Y, Gabriel G (2020). Low testosterone and high cytokine levels correlate with lethal H7N9 infections in men: a retrospective cohort study from 98 H7N9 patients. medRxiv 2020.05.07.20093914. PREPRINT

Wolff G, Limpens RWAL, Zevenhoven-Dobbe JC, Laugks U, Zheng S, de Jong AWM, Koning RI, Agard DA, Grünewald K, Koster AJ, Snijder EJ, Bárcena M (2020). A molecular pore spans the double membrane of the coronavirus replication organelle. Science. 2020 Aug 6:eabd3629.